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Parenteral Administration of Capsule Depolymerase EnvD Prevents Lethal Inhalation Anthrax Infection

Left untreated, inhalation anthrax is usually fatal. Vegetative forms of Bacillus anthracis survive in blood and tissues during infection due to elaboration of a protective poly-γ-d-glutamic acid (PDGA) capsule that permits uncontrolled bacterial growth in vivo, eventually leading to overwhelming ba...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Negus, David, Vipond, Julia, Hatch, Graham J., Rayner, Emma L., Taylor, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649238/
https://ncbi.nlm.nih.gov/pubmed/26438506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01547-15
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