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Parenteral Administration of Capsule Depolymerase EnvD Prevents Lethal Inhalation Anthrax Infection

Left untreated, inhalation anthrax is usually fatal. Vegetative forms of Bacillus anthracis survive in blood and tissues during infection due to elaboration of a protective poly-γ-d-glutamic acid (PDGA) capsule that permits uncontrolled bacterial growth in vivo, eventually leading to overwhelming ba...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Negus, David, Vipond, Julia, Hatch, Graham J., Rayner, Emma L., Taylor, Peter W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649238/
https://ncbi.nlm.nih.gov/pubmed/26438506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01547-15
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