Recombinant Anthrax Toxin Receptor-Fc Fusion Proteins Produced in Plants Protect Rabbits against Inhalational Anthrax

Inhalational anthrax, a zoonotic disease caused by the inhalation of Bacillus anthracis spores, has a ∼50% fatality rate even when treated with antibiotics. Pathogenesis is dependent on the activity of two toxic noncovalent complexes: edema toxin (EdTx) and lethal toxin (LeTx). Protective antigen (P...

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Hlavní autoři: Wycoff, Keith L., Belle, Archana, Deppe, Dorothée, Schaefer, Leah, Maclean, James M., Haase, Simone, Trilling, Anke K., Liu, Shihui, Leppla, Stephen H., Geren, Isin N., Pawlik, Jennifer, Peterson, Johnny W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019684/
https://ncbi.nlm.nih.gov/pubmed/20956592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00592-10
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