Deletion of liaR Reverses Daptomycin Resistance in Enterococcus faecium Independent of the Genetic Background

We have shown previously that changes in LiaFSR, a three-component regulatory system predicted to orchestrate the cell membrane stress response, are important mediators of daptomycin (DAP) resistance in enterococci. Indeed, deletion of the gene encoding the response regulator LiaR in a clinical stra...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Panesso, Diana, Reyes, Jinnethe, Gaston, Elizabeth P., Deal, Morgan, Londoño, Alejandra, Nigo, Masayuki, Munita, Jose M., Miller, William R., Shamoo, Yousif, Tran, Truc T., Arias, Cesar A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649183/
https://ncbi.nlm.nih.gov/pubmed/26369959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01073-15
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