LiaR-Independent Pathways to Daptomycin Resistance in Enterococcus faecalis Reveal A Multilayer Defense Against Cell Envelope Antibiotics

The lipopeptide antibiotic daptomycin (DAP) is a key drug against serious enterococcal infections, but emergence of resistance in the clinical setting is a major concern. The LiaFSR system plays a prominent role in the development of DAP resistance (DAP-R) in enterococci, and blocking this stress re...

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Bibliografske podrobnosti
izdano v:Mol Microbiol
Main Authors: Miller, William R., Tran, Truc T., Diaz, Lorena, Rios, Rafael, Khan, Ayesha, Reyes, Jinnethe, Prater, Amy G., Panesso, Diana, Shamoo, Yousif, Arias, Cesar A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417935/
https://ncbi.nlm.nih.gov/pubmed/30582877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14193
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