602. Mechanism of LiaY-Mediated Daptomycin Resistance in Enterococcus faecalis

BACKGROUND: Daptomycin (DAP) is a lipopeptide antibiotic that targets the cell membrane (CM) at the division septum. DAP resistance (DAP-R) in E. faecalis (Efs) has been linked to mutations in genes encoding the LiaFSR stress response system and lipid biosynthetic enzymes, including cardiolipin synt...

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Bibliografski detalji
Izdano u:Open Forum Infect Dis
Glavni autori: Nguyen, April, Tran, Truc T, Panesso, Diana, Khan, Ayesha, Mileykovskaya, Eugenia, Vitrac, Heidi, Arias, Cesar A
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Abstracts
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810803/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.671
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