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Eagle Effect in Nonreplicating Persister Mycobacteria
We determined the microbicidal activities of antibacterials against nonreplicating Mycobacterium smegmatis grown in a starvation-based Loebel model for persistence. Whereas most drugs lost their activity, fluoroquinolones retained lethal potency. Dose-response characterizations showed a paradoxical...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4649170/ https://ncbi.nlm.nih.gov/pubmed/26349831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01476-15 |
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