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Ribosome hibernation: a new molecular framework for targeting nonreplicating persisters of mycobacteria

Treatment of tuberculosis requires a multi-drug regimen administered for at least 6 months. The long-term chemotherapy is attributed in part to a minor subpopulation of nonreplicating Mycobacterium tuberculosis cells that exhibit phenotypic tolerance to antibiotics. The origins of these cells in inf...

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Detalles Bibliográficos
Publicado en:Microbiology (Reading)
Main Authors: Li, Yunlong, Sharma, Manjuli R., Koripella, Ravi K., Banavali, Nilesh K., Agrawal, Rajendra K., Ojha, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado: Microbiology Society 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131030/
https://ncbi.nlm.nih.gov/pubmed/33555244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.001035
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