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Eagle Effect in Nonreplicating Persister Mycobacteria

We determined the microbicidal activities of antibacterials against nonreplicating Mycobacterium smegmatis grown in a starvation-based Loebel model for persistence. Whereas most drugs lost their activity, fluoroquinolones retained lethal potency. Dose-response characterizations showed a paradoxical...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wu, Mu-Lu, Tan, Jasmie, Dick, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649170/
https://ncbi.nlm.nih.gov/pubmed/26349831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01476-15
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