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Targeting the interleukin-15/interleukin-15 receptor system in inflammatory autoimmune diseases

Interleukin (IL)-15 is a dangerous inflammatory cytokine that induces tumor-necrosis factor-α, IL-1β and inflammatory chemokines. It inhibits self-tolerance mediated by IL-2 mediated activation-induced cell death and facilitates maintenance of CD8(+ )memory T-cell survival including that of self-dir...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Author: Waldmann, Thomas A
Format: Artigo
Language:Inglês
Published: BMC 2004
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC464917/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15225362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar1202
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