Interleukin 6 plays a key role in the development of antigen-induced arthritis

To investigate the direct role of interleukin (IL) 6 in the development of rheumatoid arthritis, IL-6-deficient (IL-6 −/−) mice were backcrossed for eight generations into C57BL/6 mice, a strain of mice with a genetic background of susceptibility for antigen-induced arthritis (AIA). Both histologica...

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Detalhes bibliográficos
Main Authors: Ohshima, Shiro, Saeki, Yukihiko, Mima, Toru, Sasai, Mitsuko, Nishioka, Katsuhiro, Nomura, Shintaro, Kopf, Manfred, Katada, Yoshinori, Tanaka, Toshio, Suemura, Masaki, Kishimoto, Tadamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20957/
https://ncbi.nlm.nih.gov/pubmed/9653168
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