Interleukin 6 plays a key role in the development of antigen-induced arthritis

To investigate the direct role of interleukin (IL) 6 in the development of rheumatoid arthritis, IL-6-deficient (IL-6 −/−) mice were backcrossed for eight generations into C57BL/6 mice, a strain of mice with a genetic background of susceptibility for antigen-induced arthritis (AIA). Both histologica...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ohshima, Shiro, Saeki, Yukihiko, Mima, Toru, Sasai, Mitsuko, Nishioka, Katsuhiro, Nomura, Shintaro, Kopf, Manfred, Katada, Yoshinori, Tanaka, Toshio, Suemura, Masaki, Kishimoto, Tadamitsu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8222
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