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Targeting the interleukin-15/interleukin-15 receptor system in inflammatory autoimmune diseases

Interleukin (IL)-15 is a dangerous inflammatory cytokine that induces tumor-necrosis factor-α, IL-1β and inflammatory chemokines. It inhibits self-tolerance mediated by IL-2 mediated activation-induced cell death and facilitates maintenance of CD8(+ )memory T-cell survival including that of self-dir...

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Bibliografiske detaljer
Hovedforfatter: Waldmann, Thomas A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC464917/
https://ncbi.nlm.nih.gov/pubmed/15225362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1202
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