Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression

In the present study, we have shown for the first time that a plant steroid, diosgenin, causes an inhibition of the growth of fibroblast-like synoviocytes from human rheumatoid arthritis, with apoptosis induction associated with cyclooxygenase-2 (COX-2) up-regulation. Celecoxib, a selective COX-2 in...

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Bibliografiske detaljer
Main Authors: Liagre, Bertrand, Vergne-Salle, Pascale, Corbiere, Cecile, Charissoux, Jean L, Beneytout, Jean L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC464911/
https://ncbi.nlm.nih.gov/pubmed/15225373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1199
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