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Synthesis and dynamics studies of barbituric acid derivatives as urease inhibitors
BACKGROUND: Discovery of potent inhibitors of urease (jack bean) enzyme is the first step in the development of drugs against diseases caused by ureolytic enzyme. RESULTS: Thirty-two derivatives of barbituric acid as zwitterionic adducts of diethyl ammonium salts were synthesized. All synthesized co...
Enregistré dans:
| Publié dans: | Chem Cent J |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer International Publishing
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648982/ https://ncbi.nlm.nih.gov/pubmed/26583043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-015-0140-1 |
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