Bactericidal antibiotics induce toxic metabolic perturbations that lead to cellular damage

Understanding how antibiotics impact bacterial metabolism may provide insight into their mechanisms of action and could lead to enhanced therapeutic methodologies. Here, we profiled the metabolome of Escherichia coli after treatment with three different classes of bactericidal antibiotics (beta-lact...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Belenky, Peter, Ye, Jonathan D., Porter, Caroline B. M., Cohen, Nadia R., Lobritz, Michael A., Ferrante, Thomas, Jain, Saloni, Korry, Benjamin J., Schwarz, Eric G., Walker, Graham C., Collins, James J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648786/
https://ncbi.nlm.nih.gov/pubmed/26565910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.059
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