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Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics
A detailed understanding of the mechanisms that underlie antibiotic killing is important for the derivation of new classes of antibiotics and clinically useful adjuvants for current antimicrobial therapies. Our efforts to understand why DinB (DNA Polymerase IV) overproduction is cytotoxic to Escheri...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357493/ https://ncbi.nlm.nih.gov/pubmed/22517853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1219192 |
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