CDK11 in TREX/THOC regulates HIV mRNA 3’ end processing

Transcriptional cyclin-dependent kinases play important roles in eukaryotic gene expression. CDK7, CDK9 (P-TEFb) and CDK13 are also critical for HIV replication. However, the function of CDK11 remained enigmatic. In this report, we determined that CDK11 regulates the cleavage and polyadenylation (CP...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Pak, Vladimir, Eifler, Tristan T., Jäger, Stefanie, Krogan, Nevan J., Fujinaga, Koh, Peterlin, B. Matija
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648707/
https://ncbi.nlm.nih.gov/pubmed/26567509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.10.012
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