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Ageing, autoimmunity and arthritis: Senescence of the B cell compartment – implications for humoral immunity

Immunosenescence is associated with a decline in both T and B lymphocyte function. Although aged individuals have normal numbers of B cells in the periphery and are capable of mounting robust humoral responses, the antibodies produced are generally of lower affinity and are less protective than thos...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Johnson, Sara A, Cambier, John C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC464870/
https://ncbi.nlm.nih.gov/pubmed/15225355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1180
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