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Ageing, autoimmunity and arthritis: Senescence of the B cell compartment – implications for humoral immunity
Immunosenescence is associated with a decline in both T and B lymphocyte function. Although aged individuals have normal numbers of B cells in the periphery and are capable of mounting robust humoral responses, the antibodies produced are generally of lower affinity and are less protective than thos...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC464870/ https://ncbi.nlm.nih.gov/pubmed/15225355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1180 |
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