Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease.

During development in the mosquito midgut, malarial parasites must traverse a chitin-containing peritrophic matrix (PM) that forms around the food bolus. Previously Huber et al. [Huber, M., Cabib, E. & Miller, L. H. (1991) Proc. Natl. Acad. Sci. USA 88, 2807-2810] reported that the parasite secr...

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Autors principals: Shahabuddin, M, Toyoshima, T, Aikawa, M, Kaslow, D C
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC46487/
https://ncbi.nlm.nih.gov/pubmed/8483942
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