Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

Anti-malarial pre-erythrocytic vaccines (PEV) target transmission by inhibiting human infection but are currently partially protective. It has been posited, but never demonstrated, that co-administering transmission-blocking vaccines (TBV) would enhance malaria control. We hypothesized a mechanism t...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sherrard-Smith, Ellie, Sala, Katarzyna A, Betancourt, Michael, Upton, Leanna M, Angrisano, Fiona, Morin, Merribeth J, Ghani, Azra C, Churcher, Thomas S, Blagborough, Andrew M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Epidemiology and Global Health
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008048/
https://ncbi.nlm.nih.gov/pubmed/29914622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35213
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