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Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors

Effective control and eradication of malaria will require new tools to prevent transmission. Current antimalarial therapies targeting the asexual stage of Plasmodium do not prevent transmission of circulating gametocytes from infected humans to mosquitoes. Here, we describe a new class of transmissi...

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Hlavní autoři: Ojo, Kayode K., Pfander, Claudia, Mueller, Natascha R., Burstroem, Charlotte, Larson, Eric T., Bryan, Cassie M., Fox, Anna M.W., Reid, Molly C., Johnson, Steven M., Murphy, Ryan C., Kennedy, Mark, Mann, Henning, Leibly, David J., Hewitt, Stephen N., Verlinde, Christophe L.M.J., Kappe, Stefan, Merritt, Ethan A., Maly, Dustin J., Billker, Oliver, Van Voorhis, Wesley C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366411/
https://ncbi.nlm.nih.gov/pubmed/22565309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61822
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