Odanacatib, A Cathepsin K-Specific Inhibitor, Inhibits Inflammation and Bone Loss Caused by Periodontal Diseases

BACKGROUND: Periodontitis is a bacteria-induced inflammatory disease mainly affecting periodontal tissues, leading to periodontal inflammation, bone breakdown, and loss of the tooth. The main obstacle for treating periodontitis effectively is the difficulty in finding a target that can inhibit bone...

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Vydáno v:J Periodontol
Hlavní autoři: Hao, Liang, Chen, Jianwei, Zhu, Zheng, Reddy, Michael S., Mountz, John D., Chen, Wei, Li, Yi-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648620/
https://ncbi.nlm.nih.gov/pubmed/25879791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1902/jop.2015.140643
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