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The melanocortin system and insulin resistance in humans: insights from a patient with complete POMC deficiency and type 1 diabetes mellitus

The central melanocortin system is essential for the regulation of long-term energy homeostasis in humans. Rodent experiments suggest that this system also affects glucose metabolism, in particular by modulating peripheral insulin sensitivity independently of its effect on adiposity. Rare patients w...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Aslan, Ivy R., Ranadive, Sayali A., Valle, Inmaculada, Kollipara, Sobha, Noble, Janelle A., Vaisse, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648369/
https://ncbi.nlm.nih.gov/pubmed/23649472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2013.53
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