Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus

OBJECTIVE: The liver regulates the availability of insulin to other tissues and is the first line insulin response organ physiologically exposed to higher insulin concentrations than the periphery. Basal insulin during fasting inhibits hepatic gluconeogenesis and glycogenolysis, whereas postprandial...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Backman, Mattias, Flenkenthaler, Florian, Blutke, Andreas, Dahlhoff, Maik, Ländström, Erik, Renner, Simone, Philippou-Massier, Julia, Krebs, Stefan, Rathkolb, Birgit, Prehn, Cornelia, Grzybek, Michal, Coskun, Ünal, Rothe, Michael, Adamski, Jerzy, de Angelis, Martin Hrabĕ, Wanke, Rüdiger, Fröhlich, Thomas, Arnold, Georg J., Blum, Helmut, Wolf, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667734/
https://ncbi.nlm.nih.gov/pubmed/31221621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.05.011
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