Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma

Liposarcoma (LPS) is a type of soft tissue sarcoma that mostly occurs in adults, and in humans is characterized by amplifications of MDM2 and CDK4. The molecular pathogenesis of this malignancy is still poorly understood and, therefore, we developed a mouse model with conditional inactivation of PTE...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Puzio-Kuter, A M, Laddha, S V, Castillo-Martin, M, Sun, Y, Cordon-Cardo, C, Chan, C S, Levine, A J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648325/
https://ncbi.nlm.nih.gov/pubmed/25822339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.27
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