Mutation spectrum and risk of colorectal cancer in African American families with Lynch Syndrome

BACKGROUND & AIMS: African Americans (AAs) have the highest incidence and mortality of colorectal cancer (CRC) in the United States (US). Few data are available on genetic and non-genetic risk factors for CRC among AAs. Little is known about cancer risks and mutations in mismatch repair (MMR) ge...

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Veröffentlicht in:Gastroenterology
Hauptverfasser: Guindalini, Rodrigo Santa Cruz, Win, Aung Ko, Gulden, Cassandra, Lindor, Noralane M., Newcomb, Polly A., Haile, Robert W., Raymond, Victoria, Stoffel, Elena, Hall, Michael, Llor, Xavier, Ukaegbu, Chinedu I., Solomon, Ilana, Weitzel, Jeffrey, Kalady, Matthew, Blanco, Amie, Terdiman, Jonathan, Shuttlesworth, Gladis A., Lynch, Patrick M., Hampel, Heather, Lynch, Henry T., Jenkins, Mark A., Olopade, Olufunmilayo I., Kupfer, Sonia S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648287/
https://ncbi.nlm.nih.gov/pubmed/26248088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.07.052
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