Performance of Lynch Syndrome Predictive Models in a Multi-center US Referral Population

OBJECTIVE: Lynch syndrome is the most common cause of inherited colorectal cancer (CRC) and is due to germline mutations in mismatch repair (MMR) genes. Early Lynch syndrome diagnosis and appropriate CRC surveillance improves mortality. Traditional qualitative clinical criteria including Amsterdam a...

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Hlavní autoři: Khan, Omar, Blanco, Amie, Conrad, Peggy, Gulden, Cassandra, Moss, Tovah Z., Olopade, Olufunmilayo I., Kupfer, Sonia S., Terdiman, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804147/
https://ncbi.nlm.nih.gov/pubmed/21747416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2011.200
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