Performance of Lynch Syndrome Predictive Models in a Multi-center US Referral Population

OBJECTIVE: Lynch syndrome is the most common cause of inherited colorectal cancer (CRC) and is due to germline mutations in mismatch repair (MMR) genes. Early Lynch syndrome diagnosis and appropriate CRC surveillance improves mortality. Traditional qualitative clinical criteria including Amsterdam a...

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Bibliografiske detaljer
Main Authors: Khan, Omar, Blanco, Amie, Conrad, Peggy, Gulden, Cassandra, Moss, Tovah Z., Olopade, Olufunmilayo I., Kupfer, Sonia S., Terdiman, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804147/
https://ncbi.nlm.nih.gov/pubmed/21747416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2011.200
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