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Performance of Lynch Syndrome Predictive Models in a Multi-center US Referral Population

OBJECTIVE: Lynch syndrome is the most common cause of inherited colorectal cancer (CRC) and is due to germline mutations in mismatch repair (MMR) genes. Early Lynch syndrome diagnosis and appropriate CRC surveillance improves mortality. Traditional qualitative clinical criteria including Amsterdam a...

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Detalhes bibliográficos
Main Authors: Khan, Omar, Blanco, Amie, Conrad, Peggy, Gulden, Cassandra, Moss, Tovah Z., Olopade, Olufunmilayo I., Kupfer, Sonia S., Terdiman, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804147/
https://ncbi.nlm.nih.gov/pubmed/21747416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2011.200
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