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Diaza-anthracene Antibiotics from a Freshwater-Derived Actinomycete with Selective Antibacterial Activity toward Mycobacterium tuberculosis

Multidrug- and extensively drug-resistant strains of Mycobacterium tuberculosis are resistant to first- and second-line drug regimens and resulted in 210,000 fatalities in 2013. In the current study, we screened a library of aquatic bacterial natural product fractions for their ability to inhibit th...

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Publicado en:ACS Infect Dis
Main Authors: Mullowney, Michael W., Hwang, Chang Hwa, Newsome, Andrew G., Wei, Xiaomei, Tanouye, Urszula, Wan, Baojie, Carlson, Skylar, Barranis, Nanthida Joy, hAinmhire, EoghainínÓ, Chen, Wei-Lun, Krishnamoorthy, Kalyanaraman, White, John, Blair, Rachel, Lee, Hyunwoo, Burdette, Joanna E., Rathod, Pradipsinh K., Parish, Tanya, Cho, Sanghyun, Franzblau, Scott G., Murphy, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648258/
https://ncbi.nlm.nih.gov/pubmed/26594660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00005
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