Diazaquinomycins E–G, Novel Diaza-Anthracene Analogs from a Marine-Derived Streptomyces sp.

As part of our program to identify novel secondary metabolites that target drug-resistant ovarian cancers, a screening of our aquatic-derived actinomycete fraction library against a cisplatin-resistant ovarian cancer cell line (OVCAR5) led to the isolation of novel diaza-anthracene antibiotic diazaq...

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Detalhes bibliográficos
Main Authors: Mullowney, Michael W., Ó hAinmhire, Eoghainín, Shaikh, Anam, Wei, Xiaomei, Tanouye, Urszula, Santarsiero, Bernard D., Burdette, Joanna E., Murphy, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071591/
https://ncbi.nlm.nih.gov/pubmed/24921978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12063574
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