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Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes

Tuberculosis is an infectious disease of global concern. Members of the diazaquinomycin (DAQ) class of natural products have shown potent and selective activity against drug-resistant Mycobacterium tuberculosis. However, poor solubility has prevented further development of this compound class. Under...

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Bibliographische Detailangaben
Veröffentlicht in:J Nat Prod
Hauptverfasser: Braesel, Jana, Lee, Jung-Ho, Arnould, Benoit, Murphy, Brian T., Eustáquio, Alessandra S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902439/
https://ncbi.nlm.nih.gov/pubmed/30896942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.8b01028
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