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Toward rapamycin analog (rapalog)-based precision cancer therapy

Rapamycin and its analogs (rapalogs) are the first generation of mTOR inhibitors, which have the same molecular scaffold, but different physiochemical properties. Rapalogs are being tested in a wide spectrum of human tumors as both monotherapy and a component of combination therapy. Among them, tems...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Meng, Ling-hua, Zheng, XF Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648176/
https://ncbi.nlm.nih.gov/pubmed/26299952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.68
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