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Toward rapamycin analog (rapalog)-based precision cancer therapy

Rapamycin and its analogs (rapalogs) are the first generation of mTOR inhibitors, which have the same molecular scaffold, but different physiochemical properties. Rapalogs are being tested in a wide spectrum of human tumors as both monotherapy and a component of combination therapy. Among them, tems...

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Publicat a:Acta Pharmacol Sin
Autors principals: Meng, Ling-hua, Zheng, XF Steven
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648176/
https://ncbi.nlm.nih.gov/pubmed/26299952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.68
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