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Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates
BACKGROUND: Positron emission tomography microdosing of radiolabeled drugs allows for noninvasive studies of organ exposure in vivo. The aim of the present study was to examine and compare the brain exposure of 12 commercially available CNS drugs and one non-CNS drug. METHODS: The drugs were radiola...
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| Gepubliceerd in: | Int J Neuropsychopharmacol |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648157/ https://ncbi.nlm.nih.gov/pubmed/25813017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv036 |
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