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Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates

BACKGROUND: Positron emission tomography microdosing of radiolabeled drugs allows for noninvasive studies of organ exposure in vivo. The aim of the present study was to examine and compare the brain exposure of 12 commercially available CNS drugs and one non-CNS drug. METHODS: The drugs were radiola...

Deskribapen osoa

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Xehetasun bibliografikoak
Argitaratua izan da:Int J Neuropsychopharmacol
Egile Nagusiak: Schou, Magnus, Varnäs, Katarina, Lundquist, Stefan, Nakao, Ryuji, Amini, Nahid, Takano, Akihiro, Finnema, Sjoerd J., Halldin, Christer, Farde, Lars
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648157/
https://ncbi.nlm.nih.gov/pubmed/25813017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv036
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