Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis

Tetrahydropyran rings are a common feature of complex polyketide natural products, but much remains to be learned about the enzymology of their formation. The enzyme SalBIII from the salinomycin biosynthetic pathway resembles other polyether epoxide hydrolases/cyclases of the MonB family, but SalBII...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Luhavaya, Hanna, Dias, Marcio V B, Williams, Simon R, Hong, Hui, de Oliveira, Luciana G, Leadlay, Peter F
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2015
Fag:
Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648038/
https://ncbi.nlm.nih.gov/pubmed/26377145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507090
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