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Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis

Tetrahydropyran rings are a common feature of complex polyketide natural products, but much remains to be learned about the enzymology of their formation. The enzyme SalBIII from the salinomycin biosynthetic pathway resembles other polyether epoxide hydrolases/cyclases of the MonB family, but SalBII...

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Bibliografiset tiedot
Julkaisussa:Angew Chem Int Ed Engl
Päätekijät: Luhavaya, Hanna, Dias, Marcio V B, Williams, Simon R, Hong, Hui, de Oliveira, Luciana G, Leadlay, Peter F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: WILEY-VCH Verlag 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648038/
https://ncbi.nlm.nih.gov/pubmed/26377145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507090
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