Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis

BACKGROUND: Hypoxia leads to the stabilisation of the hypoxia-inducible factor (HIF) transcription factor that drives the expression of target genes including microRNAs (miRNAs). MicroRNAs are known to regulate many genes involved in tumourigenesis. The aim of this study was to identify hypoxia-regu...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Blick, C, Ramachandran, A, McCormick, R, Wigfield, S, Cranston, D, Catto, J, Harris, A L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647685/
https://ncbi.nlm.nih.gov/pubmed/26196183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.203
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