miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer

BACKGROUND: We have recently identified down-regulated microRNAs including miR-145 and miR-133a in bladder cancer (BC). The aim of this study is to determine the genes targeted by miR-145, which is the most down-regulated microRNA in BC. METHODS: We focused on fascin homologue 1 (FSCN1) from the gen...

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Autors principals: Chiyomaru, T, Enokida, H, Tatarano, S, Kawahara, K, Uchida, Y, Nishiyama, K, Fujimura, L, Kikkawa, N, Seki, N, Nakagawa, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833258/
https://ncbi.nlm.nih.gov/pubmed/20160723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605570
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