Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer

BACKGROUND: Our recent analyses of miRNA expression signatures showed that miR-1 and miR-133a were significantly reduced in several types of cancer. Interestingly, miR-1 and miR-133a are located on the same chromosomal locus in the human genome. We examined the functional significance of miR-1 and m...

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Detalhes bibliográficos
Main Authors: Kojima, S, Chiyomaru, T, Kawakami, K, Yoshino, H, Enokida, H, Nohata, N, Fuse, M, Ichikawa, T, Naya, Y, Nakagawa, M, Seki, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261671/
https://ncbi.nlm.nih.gov/pubmed/22068816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.462
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