Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis

BACKGROUND: Hypoxia leads to the stabilisation of the hypoxia-inducible factor (HIF) transcription factor that drives the expression of target genes including microRNAs (miRNAs). MicroRNAs are known to regulate many genes involved in tumourigenesis. The aim of this study was to identify hypoxia-regu...

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書目詳細資料
發表在:Br J Cancer
Main Authors: Blick, C, Ramachandran, A, McCormick, R, Wigfield, S, Cranston, D, Catto, J, Harris, A L
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
主題:
Molecular Diagnostics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647685/
https://ncbi.nlm.nih.gov/pubmed/26196183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.203
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