Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

BACKGROUND: Proper neuronal function requires tight control of gene dosage, and failure of this process underlies the pathogenesis of multiple neuropsychiatric disorders. The SHANK3 gene encoding core scaffolding proteins at glutamatergic postsynapse is a typical dosage-sensitive gene, both deletion...

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Dades bibliogràfiques
Publicat a:Mol Brain
Autors principals: Choi, Su-Yeon, Pang, Kaifang, Kim, Joo Yeon, Ryu, Jae Ryun, Kang, Hyojin, Liu, Zhandong, Kim, Won-Ki, Sun, Woong, Kim, Hyun, Han, Kihoon
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647645/
https://ncbi.nlm.nih.gov/pubmed/26572867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0165-3
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