Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

BACKGROUND: Proper neuronal function requires tight control of gene dosage, and failure of this process underlies the pathogenesis of multiple neuropsychiatric disorders. The SHANK3 gene encoding core scaffolding proteins at glutamatergic postsynapse is a typical dosage-sensitive gene, both deletion...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Choi, Su-Yeon, Pang, Kaifang, Kim, Joo Yeon, Ryu, Jae Ryun, Kang, Hyojin, Liu, Zhandong, Kim, Won-Ki, Sun, Woong, Kim, Hyun, Han, Kihoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647645/
https://ncbi.nlm.nih.gov/pubmed/26572867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0165-3
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