AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

BACKGROUND: AXL is a well-characterized, protumorigenic receptor tyrosine kinase that is highly expressed and activated in numerous human carcinomas and sarcomas, including aggressive subtypes of liposarcoma. However, the role of AXL in the pathogenesis of well-differentiated (WDLPS), dedifferentiat...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: May, Caitlin D., Garnett, Jeannine, Ma, XiaoYan, Landers, Sharon M., Ingram, Davis R., Demicco, Elizabeth G., Al Sannaa, Ghadah A., Vu, Tona, Han, Lixia, Zhang, Yi, Kivlin, Christine M., Bolshakov, Svetlana, Kalam, Azad Abul, Liu, Juehui, Zhou, Fuguo, Broccoli, Dominique, Wang, Wei-Lien, Lazar, Alexander J., Pollock, Raphael E., Lev, Dina, Torres, Keila E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647521/
https://ncbi.nlm.nih.gov/pubmed/26573603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1916-3
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