AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

BACKGROUND: AXL is a well-characterized, protumorigenic receptor tyrosine kinase that is highly expressed and activated in numerous human carcinomas and sarcomas, including aggressive subtypes of liposarcoma. However, the role of AXL in the pathogenesis of well-differentiated (WDLPS), dedifferentiat...

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Gepubliceerd in:BMC Cancer
Hoofdauteurs: May, Caitlin D., Garnett, Jeannine, Ma, XiaoYan, Landers, Sharon M., Ingram, Davis R., Demicco, Elizabeth G., Al Sannaa, Ghadah A., Vu, Tona, Han, Lixia, Zhang, Yi, Kivlin, Christine M., Bolshakov, Svetlana, Kalam, Azad Abul, Liu, Juehui, Zhou, Fuguo, Broccoli, Dominique, Wang, Wei-Lien, Lazar, Alexander J., Pollock, Raphael E., Lev, Dina, Torres, Keila E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647521/
https://ncbi.nlm.nih.gov/pubmed/26573603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1916-3
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