AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

BACKGROUND: AXL is a well-characterized, protumorigenic receptor tyrosine kinase that is highly expressed and activated in numerous human carcinomas and sarcomas, including aggressive subtypes of liposarcoma. However, the role of AXL in the pathogenesis of well-differentiated (WDLPS), dedifferentiat...

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Pubblicato in:BMC Cancer
Autori principali: May, Caitlin D., Garnett, Jeannine, Ma, XiaoYan, Landers, Sharon M., Ingram, Davis R., Demicco, Elizabeth G., Al Sannaa, Ghadah A., Vu, Tona, Han, Lixia, Zhang, Yi, Kivlin, Christine M., Bolshakov, Svetlana, Kalam, Azad Abul, Liu, Juehui, Zhou, Fuguo, Broccoli, Dominique, Wang, Wei-Lien, Lazar, Alexander J., Pollock, Raphael E., Lev, Dina, Torres, Keila E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647521/
https://ncbi.nlm.nih.gov/pubmed/26573603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1916-3
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