Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins

Transglutaminase (TG) catalyzes protein-protein crosslinking, which has important and diverse roles in vertebrates and invertebrates. Here we demonstrate that Drosophila TG crosslinks drosocrystallin, a peritrophic matrix protein, to form a stable fiber structure on the gut peritrophic matrix. RNA i...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Shibata, Toshio, Maki, Kouki, Hadano, Jinki, Fujikawa, Takumi, Kitazaki, Kazuki, Koshiba, Takumi, Kawabata, Shun-ichiro
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646701/
https://ncbi.nlm.nih.gov/pubmed/26506243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005244
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