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Drosophila TG-A transglutaminase is secreted via an unconventional Golgi-independent mechanism involving exosomes and two types of fatty acylations

Transglutaminases (TGs) play essential intracellular and extracellular roles by covalently cross-linking many proteins. Drosophila TG is encoded by one gene and has two alternative splicing-derived isoforms, TG-A and TG-B, which contain distinct N-terminal 46- and 38-amino acid sequences, respective...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Shibata, Toshio, Hadano, Jinki, Kawasaki, Daichi, Dong, Xiaoqing, Kawabata, Shun-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481576/
https://ncbi.nlm.nih.gov/pubmed/28476891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.779710
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