The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life

Autotaxin (ATX, Enpp2) is a secreted lysophospholipase D catalysing the production of lysophosphatidic acid, a pleiotropic growth factor-like lysophospholipid. Increased ATX expression has been detected in a number of chronic inflammatory diseases and different types of cancer, while genetic interve...

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Udgivet i:PLoS One
Main Authors: Katsifa, Aggeliki, Kaffe, Eleanna, Nikolaidou-Katsaridou, Nefeli, Economides, Aris N., Newbigging, Susan, McKerlie, Colin, Aidinis, Vassilis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646642/
https://ncbi.nlm.nih.gov/pubmed/26569406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143083
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