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Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
Rheumatoid arthritis is a destructive arthropathy characterized by chronic synovial inflammation that imposes a substantial socioeconomic burden. Under the influence of the proinflammatory milieu, synovial fibroblasts (SFs), the main effector cells in disease pathogenesis, become activated and hyper...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348105/ https://ncbi.nlm.nih.gov/pubmed/22493518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112012 |
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